BDBM608392 (Z)-15-chloro-13,21,23,61-tetramethyl-4- (methylsulfonyl)-11H,21H,61H-10-oxa-8-thia- 4-aza-1(4,1)-indola-2(4,5),6(3,5)-dipyrazola- 9(3,1)-naphthalenacyclotridecaphane-12-carboxylic acid::US11691989, Compound 48
SMILES Cc1nn(C)c2CN(Cc3cc(CSc4cc(OCCCn5c(C(O)=O)c(C)c6c(-c12)c(Cl)ccc56)c1ccccc1c4)n(C)n3)S(C)(=O)=O
InChI Key InChIKey=STNUNNKZHWWPOE-UHFFFAOYSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 608392
TargetInduced myeloid leukemia cell differentiation protein Mcl-1 [171-323](Homo sapiens (Human))
Ascentage Pharma (Suzhou)
US Patent
Ascentage Pharma (Suzhou)
US Patent
Affinity DataIC50: 12nMAssay Description:The relative binding potency of representative Compounds of the Disclosure was determined by a fluorescence polarization (FP) assay. The method used ...More data for this Ligand-Target Pair