BDBM608394 (Z)-15-chloro-96-fluoro-4-(2-methoxyethyl)- 13,61-dimethyl-26,27-dihydro-11H,24H,61H-10- oxa-8-thia-4-aza-2(3,2)-pyrazolo[5,1- c][1,4]oxazina-1(4,1)-indola-6(3,5)-pyrazola- 9(3,1)-naphthalenacyclotridecaphane-12-carboxylic acid::US11691989, Compound 50

SMILES COCCN1Cc2cc(CSc3cc(OCCCn4c(C(O)=O)c(C)c5c(-c6c(C1)nn1CCOCc61)c(Cl)ccc45)c1ccc(F)cc1c3)n(C)n2

InChI Key InChIKey=HJLDIRUMFICUBV-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 608394   

TargetInduced myeloid leukemia cell differentiation protein Mcl-1 [171-323](Human)
Ascentage Pharma (Suzhou)

US Patent
LigandPNGBDBM608394((Z)-15-chloro-96-fluoro-4-(2-methoxyethyl)- 13,61-...)
Affinity DataIC50:  20nMAssay Description:The relative binding potency of representative Compounds of the Disclosure was determined by a fluorescence polarization (FP) assay. The method used ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent