BDBM608395 (Z)-15-chloro-96-fluoro-13,61-dimethyl-4-(2- (methylsulfonamido)ethyl)-26,27-dihydro- 11H,24H,61H-10-oxa-8-thia-4-aza-2(3,2)- pyrazolo[5,1-c][1,4]oxazina-1(4,1)-indola- 6(3,5)-pyrazola-9(3,1)- naphthalenacyclotridecaphane-12-carboxylic acid::US11691989, Compound 51

SMILES Cc1c(C(O)=O)n2CCCOc3cc(SCc4cc(CN(CCNS(C)(=O)=O)CC5=C(C6=[N](CCOC6)N5)c5c(Cl)ccc2c15)nn4C)cc1cc(F)ccc31

InChI Key InChIKey=LURBGGIIOQOOBF-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 608395   

TargetInduced myeloid leukemia cell differentiation protein Mcl-1 [171-323](Human)
Ascentage Pharma (Suzhou)

US Patent
LigandPNGBDBM608395((Z)-15-chloro-96-fluoro-13,61-dimethyl-4-(2- (meth...)
Affinity DataIC50:  17nMAssay Description:The relative binding potency of representative Compounds of the Disclosure was determined by a fluorescence polarization (FP) assay. The method used ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent