BDBM608398 (Z)-15-chloro-4-(2-(dimethylamino)-2- oxoethyl)-96-fluoro-13,21,25,61-tetramethyl- 11H,21H,61H-10-oxa-8-thia-4-aza-1(4,1)- indola-2(4,3),6(3,5)-dipyrazola-9(3,1)- naphthalenacyclotridecaphane-12-carboxylic acid::US11691989, Compound 54

SMILES CN(C)C(=O)CN1Cc2cc(CSc3cc(OCCCn4c(C(O)=O)c(C)c5c(-c6c(C)n(C)nc6C1)c(Cl)ccc45)c1ccc(F)cc1c3)n(C)n2

InChI Key InChIKey=FGEWKRDXWVLVIB-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 608398   

TargetInduced myeloid leukemia cell differentiation protein Mcl-1 [171-323](Human)
Ascentage Pharma (Suzhou)

US Patent
LigandPNGBDBM608398((Z)-15-chloro-4-(2-(dimethylamino)-2- oxoethyl)-96...)
Affinity DataIC50:  27nMAssay Description:The relative binding potency of representative Compounds of the Disclosure was determined by a fluorescence polarization (FP) assay. The method used ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent