BDBM609719 BDBM609735::DOTA-Gly-Gly- Val-D-Ala- boroPro::US11707539, Compound 6522::US20240207292, Compound 6522

SMILES CC(C)[C@H](NC(=O)CNC(=O)CNC(=O)CN1CCN(CC(O)=O)CCN(CC(O)=O)CCN(CC(O)=O)CC1)C(=O)N[C@H](C)C(=O)N1CCC[C@H]1B(O)O

InChI Key InChIKey=MHFTVQPOSPZQHI-UHFFFAOYSA-N

Data  11 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 609719   

TargetProlyl endopeptidase FAP(Human)
Tufts College

US Patent
LigandPNGBDBM609719(DOTA-Gly-Gly- Val-D-Ala- boroPro | US11707539, Com...)
Affinity DataIC50: 3.5nMAssay Description:Enzymatic activity of DPPIV, DPP8, DPP9, FAP, and PREP was measured at 25° C. on a Molecular Devices M2e multidetection microtiter plate reader, moni...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2024
Entry Details
US Patent

TargetProlyl endopeptidase FAP(Human)
Tufts College

US Patent
LigandPNGBDBM609719(DOTA-Gly-Gly- Val-D-Ala- boroPro | US11707539, Com...)
Affinity DataIC50: 3.5nMAssay Description:The purpose of this assay is to determine the IC50 of various inhibitors against recombinant human dipeptidyl peptidase IV (DPPIV), fibroblast activa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2023
Entry Details
US Patent

TargetProlyl endopeptidase(Human)
Tufts College

US Patent
LigandPNGBDBM609719(DOTA-Gly-Gly- Val-D-Ala- boroPro | US11707539, Com...)
Affinity DataIC50: 7.60nMAssay Description:The purpose of this assay is to determine the IC50 of various inhibitors against recombinant human dipeptidyl peptidase IV (DPPIV), fibroblast activa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2023
Entry Details
US Patent

TargetProlyl endopeptidase FAP(Human)
Tufts College

US Patent
LigandPNGBDBM609719(DOTA-Gly-Gly- Val-D-Ala- boroPro | US11707539, Com...)
Affinity DataIC50: 12nMAssay Description:Enzymatic activity of DPPIV, DPP8, DPP9, FAP, and PREP was measured at 25° C. on a Molecular Devices M2e multidetection microtiter plate reader, moni...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2024
Entry Details
US Patent

TargetProlyl endopeptidase FAP(Human)
Tufts College

US Patent
LigandPNGBDBM609719(DOTA-Gly-Gly- Val-D-Ala- boroPro | US11707539, Com...)
Affinity DataIC50: 12nMAssay Description:The purpose of this assay is to determine the IC50 of various inhibitors against recombinant human dipeptidyl peptidase IV (DPPIV), fibroblast activa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2023
Entry Details
US Patent

TargetDipeptidyl peptidase 4(Human)
Tufts College

US Patent
LigandPNGBDBM609719(DOTA-Gly-Gly- Val-D-Ala- boroPro | US11707539, Com...)
Affinity DataIC50: 3.40E+3nMAssay Description:The purpose of this assay is to determine the IC50 of various inhibitors against recombinant human dipeptidyl peptidase IV (DPPIV), fibroblast activa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2023
Entry Details
US Patent

TargetPresequence protease, mitochondrial(Human)
Tufts College

US Patent
LigandPNGBDBM609719(DOTA-Gly-Gly- Val-D-Ala- boroPro | US11707539, Com...)
Affinity DataIC50: 1.30E+4nMAssay Description:Enzymatic activity of DPPIV, DPP8, DPP9, FAP, and PREP was measured at 25° C. on a Molecular Devices M2e multidetection microtiter plate reader, moni...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2024
Entry Details
US Patent

TargetProlyl endopeptidase(Human)
Tufts College

US Patent
LigandPNGBDBM609719(DOTA-Gly-Gly- Val-D-Ala- boroPro | US11707539, Com...)
Affinity DataIC50: 1.30E+4nMAssay Description:The purpose of this assay is to determine the IC50 of various inhibitors against recombinant human dipeptidyl peptidase IV (DPPIV), fibroblast activa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2023
Entry Details
US Patent

TargetDipeptidyl peptidase 4(Human)
Tufts College

US Patent
LigandPNGBDBM609719(DOTA-Gly-Gly- Val-D-Ala- boroPro | US11707539, Com...)
Affinity DataIC50: 1.00E+5nMAssay Description:Enzymatic activity of DPPIV, DPP8, DPP9, FAP, and PREP was measured at 25° C. on a Molecular Devices M2e multidetection microtiter plate reader, moni...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2024
Entry Details
US Patent

TargetDipeptidyl peptidase 4(Human)
Tufts College

US Patent
LigandPNGBDBM609719(DOTA-Gly-Gly- Val-D-Ala- boroPro | US11707539, Com...)
Affinity DataIC50: 1.00E+5nMAssay Description:The purpose of this assay is to determine the IC50 of various inhibitors against recombinant human dipeptidyl peptidase IV (DPPIV), fibroblast activa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2023
Entry Details
US Patent

TargetProlyl endopeptidase FAP(Human)
Tufts College

US Patent
LigandPNGBDBM609719(DOTA-Gly-Gly- Val-D-Ala- boroPro | US11707539, Com...)
Affinity DataIC50: 1.00E+5nMAssay Description:The purpose of this assay is to determine the IC50 of various inhibitors against recombinant human dipeptidyl peptidase IV (DPPIV), fibroblast activa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2023
Entry Details
US Patent