BDBM610105 US8168651, Compound TABLE 15.32::US8168651, Compound TABLE 15.33

SMILES CC(C)(C)OC(=O)NC1CCN(C(=O)c2ccc3c(c2)[nH]c(=O)c2ccsc23)CC1

InChI Key InChIKey=DCXFFKWZRLNCMY-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 610105   

TargetCasein kinase II subunit alpha(Human)
Cylene Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 610105BDBM610105(US8168651, Compound TABLE 15.32 | US8168651, Compo...)
Affinity DataIC50: 8.23E+6nMAssay Description:Test compounds in aqueous solution were added at a volume of 10 microliters, to a reaction mixture comprising 10 microliters Assay Dilution Buffer (A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2023
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Cylene Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 610105BDBM610105(US8168651, Compound TABLE 15.32 | US8168651, Compo...)
Affinity DataIC50: 8.23E+6nMAssay Description:PARP assays are conducted using a chemiluminescent PARP assay kit (Trevigen). Briefly, reactions are performed in Histone-coated strip wells, by addi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2023
Entry Details
US Patent

TargetCasein kinase II subunit alpha(Human)
Cylene Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 610105BDBM610105(US8168651, Compound TABLE 15.32 | US8168651, Compo...)
Affinity DataIC50: 8.23E+6nMAssay Description:Test compounds in aqueous solution were added at a volume of 10 microliters, to a reaction mixture comprising 10 microliters Assay Dilution Buffer (A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2023
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Cylene Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 610105BDBM610105(US8168651, Compound TABLE 15.32 | US8168651, Compo...)
Affinity DataIC50: 8.23E+6nMAssay Description:PARP assays are conducted using a chemiluminescent PARP assay kit (Trevigen). Briefly, reactions are performed in Histone-coated strip wells, by addi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2023
Entry Details
US Patent