BDBM613494 US11731943, Example 235::US11731943, Example 236::methyl N-[4-carbamoyl-1-[4- (cyanomethyl)-3-fluoro-1-[(4- phenylcyclohexyl)methyl]-4- piperidyl]pyrazol-3-yl]carbamate
SMILES COC(=O)Nc1nn(cc1C(N)=O)C1(CC#N)CCN(CC2CCC(CC2)c2ccccc2)CC1F
InChI Key InChIKey=XTEBMFJZHAFTNZ-UHFFFAOYSA-N
Data 4 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 613494
Affinity DataKi: 0.210nMAssay Description:The activity of the isolated recombinant JAK1 and JAK2 kinase domain was measured by monitoring phosphorylation of a peptide derived from JAK3 (Val-A...More data for this Ligand-Target Pair
Affinity DataKi: 0.320nMAssay Description:The activity of the isolated recombinant JAK1 and JAK2 kinase domain was measured by monitoring phosphorylation of a peptide derived from JAK3 (Val-A...More data for this Ligand-Target Pair
Affinity DataKi: 0.670nMAssay Description:The activity of the isolated recombinant JAK1 and JAK2 kinase domain was measured by monitoring phosphorylation of a peptide derived from JAK3 (Val-A...More data for this Ligand-Target Pair
Affinity DataKi: 1.40nMAssay Description:The activity of the isolated recombinant JAK1 and JAK2 kinase domain was measured by monitoring phosphorylation of a peptide derived from JAK3 (Val-A...More data for this Ligand-Target Pair