BDBM613503 US11731943, Example 244::methyl N-[4-carbamoyl-1-[4- (cyanomethyl)-3-fluoro-1-[[4-(3- furyl)-3-hydroxy- phenyl]methyl]-4- piperidyl]pyrazol-3-yl]carbamate
SMILES COC(=O)Nc1nn(cc1C(N)=O)C1(CC#N)CCN(Cc2ccc(-c3ccoc3)c(O)c2)CC1F
InChI Key InChIKey=GWKPEYFGVWQTFV-UHFFFAOYSA-N
Data 2 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 613503
Affinity DataKi: 0.200nMAssay Description:The activity of the isolated recombinant JAK1 and JAK2 kinase domain was measured by monitoring phosphorylation of a peptide derived from JAK3 (Val-A...More data for this Ligand-Target Pair
Affinity DataKi: 0.370nMAssay Description:The activity of the isolated recombinant JAK1 and JAK2 kinase domain was measured by monitoring phosphorylation of a peptide derived from JAK3 (Val-A...More data for this Ligand-Target Pair