BDBM613743 1-(2,2-dimethylpropyl)-3-(2- ethylaminobenzoxazol-5-yl)-1H- pyrazolo[3,4-d]pyrimidine-4,6- diamine::US11731973, Example 11

SMILES CCNc1nc2cc(ccc2o1)-c1nn(CC(C)(C)C)c2nc(N)nc(N)c12

InChI Key InChIKey=NTGXQKAUXNKBFE-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 613743   

TargetSerine/threonine-protein kinase mTOR(Human)
Galderma Research & Development

US Patent
LigandPNGBDBM613743(1-(2,2-dimethylpropyl)-3-(2- ethylaminobenzoxazol-...)
Affinity DataKi:  0.800nMAssay Description:The model for screening the inhibitory activity of the molecules on mTOR was developed with the LANTHASCREEN™ technology (Lifetechnologies). The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2023
Entry Details
US Patent