BDBM614813 A7-3-1 rel-(R)-2-(4-(((6-(cyclopropyl((5- (trifluoromethyl)pyridin-2- yl)methyl)amino)-5- fluoropyrimidin-4- yl)amino)methyl)-3,3- difluoropiperidin-1-yl)acetamide 1st eluting isomer::US20230271937, Example A7-3-1

SMILES NC(=O)CN1CC[C@@H](CNc2ncnc(N(Cc3ccc(cn3)C(F)(F)F)C3CC3)c2F)C(F)(F)C1

InChI Key InChIKey=ZTHXYVJQPFWTKV-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 614813   

TargetPeroxisome proliferator-activated receptor gamma(Human)
Nuevolution

US Patent
LigandPNGBDBM614813(US20230271937, Example A7-3-1 | A7-3-1 rel-(R)-2-(...)
Affinity DataEC50:  44nMAssay Description:The HEK293 cell line is co-transfected transiently with two plasmids, one with the RORγ ligand-binding domain fused to galactose-responsive tran...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2023
Entry Details
US Patent