BDBM614870 A7-29-1 rel-2-((3R,4R)-4-(((6- (cyclopropyl((6-(1,1- difluoroethyl)pyridin-3- yl)methyl)amino)-5- fluoropyrimidin-4- yl)amino)methyl)-3- hydroxypiperidin-1-yl)acetamide 1st eluting isomer::US20230271937, Example A7-29-1

SMILES CC(F)(F)c1ccc(CN(C2CC2)c2ncnc(NC[C@@H]3CCN(CC(N)=O)C[C@H]3O)c2F)cn1

InChI Key InChIKey=NQQFRNRWSRZHIH-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 614870   

TargetPeroxisome proliferator-activated receptor gamma(Human)
Nuevolution

US Patent
LigandChemical structure of BindingDB Monomer ID 614870BDBM614870(US20230271937, Example A7-29-1 | A7-29-1 rel-2-((3...)
Affinity DataEC50:  35nMAssay Description:The HEK293 cell line is co-transfected transiently with two plasmids, one with the RORγ ligand-binding domain fused to galactose-responsive tran...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2023
Entry Details
US Patent