BDBM614873 A7-31 rac-2-((3R,4R)-4-(((5-fluoro-6- (((1r,3S)-3-fluorocyclobutyl)(4- (trifluoromethyl)benzyl)amino) pyrimidin-4-yl)amino)methyl)-3- hydroxypiperidin-1-yl)acetamide::US20230271937, Example A7-31

SMILES NC(=O)CN1CC[C@@H](CNc2ncnc(N(Cc3ccc(C(F)F)cc3)[C@H]3C[C@H](F)C3)c2F)[C@H](O)C1

InChI Key InChIKey=KZXRNTUGXQELEJ-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 614873   

TargetPeroxisome proliferator-activated receptor gamma(Human)
Nuevolution

US Patent
LigandChemical structure of BindingDB Monomer ID 614873BDBM614873(US20230271937, Example A7-31 | A7-31 rac-2-((3R,4R...)
Affinity DataEC50:  29nMAssay Description:The HEK293 cell line is co-transfected transiently with two plasmids, one with the RORγ ligand-binding domain fused to galactose-responsive tran...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2023
Entry Details
US Patent