BDBM614886 A7-45 2-(4-(((6-(cyclopropyl((6- (trifluoromethyl)pyridin-3- yl)methyl)amino)-5- fluoropyrimidin-4- yl)amino)methyl)-4- (hydroxymethyl)piperidin-1- yl)acetamide::US20230271937, Example A7-45

SMILES NC(=O)CN1CCC(CO)(CNc2ncnc(N(Cc3ccc(nc3)C(F)(F)F)C3CC3)c2F)CC1

InChI Key InChIKey=JGXQXPDPMJSDCU-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 614886   

TargetPeroxisome proliferator-activated receptor gamma(Human)
Nuevolution

US Patent
LigandChemical structure of BindingDB Monomer ID 614886BDBM614886(US20230271937, Example A7-45 | A7-45 2-(4-(((6-(cy...)
Affinity DataEC50:  46nMAssay Description:The HEK293 cell line is co-transfected transiently with two plasmids, one with the RORγ ligand-binding domain fused to galactose-responsive tran...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2023
Entry Details
US Patent