BDBM614893 A7-52 2-(4-(((6-(cyclopropyl((5- (trifluoromethyl)pyridin-2- yl)methyl)amino)-5- fluoropyrimidin-4- yl)amino)methyl)-4- (hydroxymethyl)piperidin-1- yl)acetamide::US20230271937, Example A7-52

SMILES NC(=O)CN1CCC(CO)(CNc2ncnc(N(Cc3ccc(cn3)C(F)(F)F)C3CC3)c2F)CC1

InChI Key InChIKey=YPAVRBLZIGVBOA-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 614893   

TargetPeroxisome proliferator-activated receptor gamma(Human)
Nuevolution

US Patent
LigandPNGBDBM614893(US20230271937, Example A7-52 | A7-52 2-(4-(((6-(cy...)
Affinity DataEC50:  42nMAssay Description:The HEK293 cell line is co-transfected transiently with two plasmids, one with the RORγ ligand-binding domain fused to galactose-responsive tran...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2023
Entry Details
Go to US Patent