BDBM614928 Synthesis of 2-(4-(((6-(cyclopropyl(4-(trifluoromethyl)benzyl)amino)-5-fluoropyrimidin-4-yl)amino)methyl)-4-(1H-imidazol-2-yl)piperidin-1-yl)acetamide, A7-84::US20230271937, Example A7-84

SMILES NC(=O)CN1CCC(CNc2ncnc(N(Cc3ccc(C(F)(F)F)cc3)C3CC3)c2F)(c2ncc[nH]2)CC1

InChI Key InChIKey=FXEBLTRBWQXRQO-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 614928   

TargetPeroxisome proliferator-activated receptor gamma(Human)
Nuevolution

US Patent
LigandChemical structure of BindingDB Monomer ID 614928BDBM614928(US20230271937, Example A7-84 | 2-(4-(((6-(cyclopro...)
Affinity DataEC50:  301nMAssay Description:The HEK293 cell line is co-transfected transiently with two plasmids, one with the RORγ ligand-binding domain fused to galactose-responsive tran...More data for this Ligand-Target Pair
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Date in BDB:
10/15/2023
Entry Details
US Patent