BDBM614936 B4-2-1-1 2-(4-(((6-(cyclopropyl(4- (trifluoromethyl)benzyl)amino)-5- fluoropyrimidin-4- yl)amino)methyl)-3-hydroxy-4- methylpiperidin-1-yl)acetamide 1st eluting isomer::US20230271937, Example B4-2-1-1

SMILES CC1(CNc2ncnc(N(Cc3ccc(cc3)C(F)(F)F)C3CC3)c2F)CCN(CC(N)=O)C[C@H]1O

InChI Key InChIKey=GIKDUNNJLUOVMA-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 614936   

TargetPeroxisome proliferator-activated receptor gamma(Human)
Nuevolution

US Patent
LigandPNGBDBM614936(US20230271937, Example B4-2-1-1 | B4-2-1-1 2-(4-((...)
Affinity DataEC50:  7.5nMAssay Description:The HEK293 cell line is co-transfected transiently with two plasmids, one with the RORγ ligand-binding domain fused to galactose-responsive tran...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2023
Entry Details
US Patent