BDBM614999 US20230271939, Example 37

SMILES COc1ncc(Cl)cc1S(=O)(=O)Nc1nccc(C#Cc2cnc3[nH]nc(OC)c3c2)c1F

InChI Key InChIKey=ACTVQBZRAIHCHM-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 614999   

TargeteIF-2-alpha kinase GCN2(Human)
IP2IPO Innovations

US Patent
LigandChemical structure of BindingDB Monomer ID 614999BDBM614999(US20230271939, Example 37)
Affinity DataKi:  0.300nMAssay Description:The inhibitory activity of the Example compounds towards GCN2 enzyme was measured according to the description below, using a LanthaScreen TR-FRET (T...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2023
Entry Details
US Patent

TargeteIF-2-alpha kinase GCN2(Human)
IP2IPO Innovations

US Patent
LigandChemical structure of BindingDB Monomer ID 614999BDBM614999(US20230271939, Example 37)
Affinity DataIC50: 20.9nMAssay Description:The inhibitory activity of the Example compounds towards GCN2 enzyme was measured according to the description below, using a LanthaScreen TR-FRET (T...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2023
Entry Details
US Patent