BDBM615106 US20230271945, Compound 25

SMILES Fc1cc(F)c2[nH]c(c(CCC(=O)N[C@H]3CCNC3=O)c2c1)-c1ccccc1

InChI Key InChIKey=ZAESTKVBSLOHJM-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 615106   

TargetApolipoprotein L1(Human)
Vertex Pharmaceuticals

US Patent
LigandPNGBDBM615106(US20230271945, Compound 25)
Affinity DataIC50: 600nMAssay Description:Apolipoprotein L1 (APOL1) proteins form potassium-permeable cation pores in the plasma membrane. APOL1 risk variants (G1 and G2) induce greater potas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2023
Entry Details
US Patent