BDBM616082 US20230271964, Example 1-39::US20230271964, Example 1-47

SMILES Cc1ocnc1Cn1nc2c(-c3cc(C)nc(CO)c3)c(nc(N)n2c1=O)-c1ccccc1

InChI Key InChIKey=FFJBFKGBZAIADA-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 616082   

TargetAdenosine receptor A2a(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM616082(US20230271964, Example 1-39 | US20230271964, Examp...)
Affinity DataKi:  0.316nMAssay Description:Inhibition binding assays were performed using 0.2 µg of membranes prepared from HEK293 cells infected with BacMam human adenosine A2A receptor or 1....More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAdenosine receptor A2a(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM616082(US20230271964, Example 1-39 | US20230271964, Examp...)
Affinity DataKi:  0.316nMAssay Description:Inhibition binding assays were performed using 0.2 µg of membranes prepared from HEK293 cells infected with BacMam human adenosine A2A receptor or 1....More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAdenosine receptor A1(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM616082(US20230271964, Example 1-39 | US20230271964, Examp...)
Affinity DataKi:  158nMAssay Description:Inhibition binding assays were performed using 0.2 µg of membranes prepared from HEK293 cells infected with BacMam human adenosine A2A receptor or 1....More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAdenosine receptor A1(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM616082(US20230271964, Example 1-39 | US20230271964, Examp...)
Affinity DataKi:  158nMAssay Description:Inhibition binding assays were performed using 0.2 µg of membranes prepared from HEK293 cells infected with BacMam human adenosine A2A receptor or 1....More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent