BDBM616452 US20230278983, Code AB1135

SMILES CC(=O)c1[nH]c2ccc(F)cc2c1-c1cn(CC2CCN(CCNS(=O)(=O)c3ccc(CC(C)C)cc3)CC2)nn1

InChI Key InChIKey=TUPJAKZMYMROFB-UHFFFAOYSA-N

Data  2 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 616452   

TargetCasein kinase II subunit alpha(Human)
Universite Claude Bernard Lyon 1

US Patent
LigandChemical structure of BindingDB Monomer ID 616452BDBM616452(US20230278983, Code AB1135)
Affinity DataIC50: 48nMAssay Description:All kinase assays were performed as previously described5 at −4° C. in a final volume of 18 μL, containing 2 μL of compounds accordin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2023
Entry Details
US Patent

TargetCasein kinase II subunit alpha(Human)
Universite Claude Bernard Lyon 1

US Patent
LigandChemical structure of BindingDB Monomer ID 616452BDBM616452(US20230278983, Code AB1135)
Affinity DataIC50: 60nMAssay Description:Inhibition of full length human recombinant CK2alpha expressed in Sf21 cells using RRREDEESDDE peptide as substrate incubated for 40 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetCasein kinase II subunit alpha(Human)
Universite Claude Bernard Lyon 1

US Patent
LigandChemical structure of BindingDB Monomer ID 616452BDBM616452(US20230278983, Code AB1135)
Affinity DataKd:  90nMAssay Description:Binding affinity to full length human recombinant CK2alpha assessed as dissociation constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed