BDBM621013 6-((4-(benzothiazole-6-yl)-5-fluoropyrimidine-2-yl)amino)pyridine-3-yl)(piperazine-1-yl)ketone hydrochloride::US20230303553, Example 6

SMILES Fc1cnc(Nc2ccc(cn2)C(=O)N2CCNCC2)nc1-c1ccc2ncsc2c1

InChI Key InChIKey=GLXOBAUWZZUWAU-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 621013   

TargetDual specificity tyrosine-phosphorylation-regulated kinase 2(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM621013(US20230303553, Example 6 | 6-((4-(benzothiazole-6-...)
Affinity DataIC50: 31nMAssay Description:Inhibition of DYRK2 (unknown origin) incubated for 120 mins in presence of 33P-ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2024
Entry Details
PubMed
TargetCyclin-dependent kinase 6(Human)
Jiangsu Tasly Diyi Pharmaceutical

US Patent
LigandPNGBDBM621013(US20230303553, Example 6 | 6-((4-(benzothiazole-6-...)
Affinity DataIC50: 104nMAssay Description:Table 1: In the test plate, protein kinase, Ulight-labeled polypeptide substrate, ATP, and the compounds were mixed and the reaction was incubated. E...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2023
Entry Details
US Patent