BDBM621020 US20230303553, Example 26::tert-butyl 4-(6-((4-(2-(cyclopentylamino)benzothiazole-6-yl)-5-fluoropyrimidine-2-yl)amino)pyridine-3-yl)piperazine-1 -carboxylate

SMILES CC(C)(C)OC(=O)N1CCN(CC1)c1ccc(Nc2ncc(F)c(n2)-c2ccc3nc(NC4CCCC4)sc3c2)nc1

InChI Key InChIKey=XWBPXBNSMOXMLC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 621020   

TargetCyclin-dependent kinase 6(Human)
Jiangsu Tasly Diyi Pharmaceutical

US Patent
LigandPNGBDBM621020(US20230303553, Example 26 | tert-butyl 4-(6-((4-(2...)
Affinity DataIC50: 1.00E+3nMAssay Description:Table 1: In the test plate, protein kinase, Ulight-labeled polypeptide substrate, ATP, and the compounds were mixed and the reaction was incubated. E...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2023
Entry Details
US Patent

TargetDual specificity tyrosine-phosphorylation-regulated kinase 2(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM621020(US20230303553, Example 26 | tert-butyl 4-(6-((4-(2...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of DYRK2 (unknown origin) incubated for 120 mins in presence of 33P-ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2024
Entry Details
PubMed