BDBM622389 US20230312576, Compound 18

SMILES Cc1c[nH]c2ncnc(C3=CCN(CC3)C(=O)Nc3cccc(c3)-c3ccncc3)c12

InChI Key InChIKey=OCBHBDFZDUADJS-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 622389   

TargetLIM domain kinase 1(Human)
University of Orleans

Curated by ChEMBL
LigandPNGBDBM622389(US20230312576, Compound 18)
Affinity DataKi:  54nMAssay Description:Inhibition of LIMK1 (unknown origin) assessed as inhibition constant by LanthScreen Eu kinase binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetLIM domain kinase 1(Human)
University of Orleans

Curated by ChEMBL
LigandPNGBDBM622389(US20230312576, Compound 18)
Affinity DataKi:  54nMAssay Description:Inhibition of LIMK1 and LIMK2. Inhibition of LIMK1 and LIMK2 was measured with Lanthascreen Eu binding assay (Life Technologies). This TR-FRET assay ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2023
Entry Details
US Patent

TargetLIM domain kinase 2(Human)
Centre National De La Recherche Scientifique

US Patent
LigandPNGBDBM622389(US20230312576, Compound 18)
Affinity DataKi:  128nMAssay Description:Inhibition of LIMK1 and LIMK2. Inhibition of LIMK1 and LIMK2 was measured with Lanthascreen Eu binding assay (Life Technologies). This TR-FRET assay ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2023
Entry Details
US Patent

TargetLIM domain kinase 2(Human)
Centre National De La Recherche Scientifique

US Patent
LigandPNGBDBM622389(US20230312576, Compound 18)
Affinity DataKi:  128nMAssay Description:Inhibition of LIMK2 (unknown origin) assessed as inhibition constant by LanthScreen Eu kinase binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed