BDBM622445 US20230312576, Compound 122

SMILES CN(C)C(=O)Oc1cccc(NC(=O)N2CCC(=CC2)c2ncnc3[nH]c4CCCc4c23)c1

InChI Key InChIKey=JBWCXUIDKXVDBB-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 622445   

TargetLIM domain kinase 2(Human)
Centre National De La Recherche Scientifique

US Patent
LigandPNGBDBM622445(US20230312576, Compound 122)
Affinity DataKi:  4.02nMAssay Description:Inhibition of LIMK1 and LIMK2. Inhibition of LIMK1 and LIMK2 was measured with Lanthascreen Eu binding assay (Life Technologies). This TR-FRET assay ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetLIM domain kinase 1(Human)
Centre National De La Recherche Scientifique

US Patent
LigandPNGBDBM622445(US20230312576, Compound 122)
Affinity DataKi:  7.11nMAssay Description:Inhibition of LIMK1 and LIMK2. Inhibition of LIMK1 and LIMK2 was measured with Lanthascreen Eu binding assay (Life Technologies). This TR-FRET assay ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent