BDBM622500 US20230312582, Example Control

SMILES c1ccc2c(c1)CC(C2)Nc3ncc4c(n3)CN(C4)C(=O)COCCc5cnn[nH]5

InChI Key InChIKey=ILOFWCAZDNILKY-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 622500   

TargetAutotaxin(Human)
Wuhan Humanwell Innovative Drug Research and Development Center

US Patent
LigandPNGBDBM622500(US20230312582, Example Control | US12221449, Contr...)
Affinity DataIC50: 2.60nMAssay Description:The inhibitory activity of the compound against the Autotaxin enzyme was detected using the Autotaxin Inhibitor Screening Assay Kit (Cayman, 700580)....More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2023
Entry Details
US Patent

TargetAutotaxin(Human)
Wuhan Humanwell Innovative Drug Research and Development Center

US Patent
LigandPNGBDBM622500(US20230312582, Example Control | US12221449, Contr...)
Affinity DataIC50: 2.60nMAssay Description:The inhibitory activities of the compounds on the autotaxin enzyme were detected using the Autotaxin Inhibitor Screening Assay Kit (Cayman, 700580). ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/15/2025
Entry Details
US Patent

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Wuhan Humanwell Innovative Drug Research And Development Center

US Patent
LigandPNGBDBM622500(US20230312582, Example Control | US12221449, Contr...)
Affinity DataIC50: 6.69E+3nMAssay Description:Full-automatic electrophysiological patch clamp QPatch was used to detect the inhibitory effect of compounds on hERG. Cells used in this test were CH...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/15/2025
Entry Details
US Patent