BDBM625275 2-(4-fluorophenyl)-N-[4-(5-methyl-4-oxo-3-phenyl-4,5-dihydro-1H-pyrrolo[3,2-c]pyridin-2-yl)pyridin-2-yl]propanamide (Racemate)::US20230322767, Example 103::US20230322767, Example 104::US20230322767, Example 105

SMILES CC(C(=O)Nc1cc(ccn1)-c1[nH]c2ccn(C)c(=O)c2c1-c1ccccc1)c1ccc(F)cc1

InChI Key InChIKey=OUQRCKNQVHENIF-UHFFFAOYSA-N

Data  9 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 625275   

TargetCasein kinase I isoform alpha(Human)
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM625275(US20230322767, Example 104 | 2-(4-fluorophenyl)-N-...)
Affinity DataIC50: 0.710nMAssay Description:Recombinant fusion protein of N-terminal Glutathion-S-Transferase (GST) and full-length human CSNK1A1, expressed by baculovirus infected insect cells...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2023
Entry Details
US Patent

TargetCasein kinase I isoform delta(Human)
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM625275(US20230322767, Example 104 | 2-(4-fluorophenyl)-N-...)
Affinity DataIC50: 1.5nMAssay Description:Recombinant fusion protein of N-terminal Glutathion-S-Transferase (GST) and full-length human CSNK1D, expressed by baculovirus infected insect cells ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2023
Entry Details
US Patent

TargetCasein kinase I isoform alpha(Human)
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM625275(US20230322767, Example 104 | 2-(4-fluorophenyl)-N-...)
Affinity DataIC50: 5nMAssay Description:Recombinant fusion protein of N-terminal Glutathion-S-Transferase (GST) and full-length human CSNK1A1, expressed by baculovirus infected insect cells...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2023
Entry Details
US Patent

TargetCasein kinase I isoform delta(Human)
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM625275(US20230322767, Example 104 | 2-(4-fluorophenyl)-N-...)
Affinity DataIC50: 5.10nMAssay Description:Recombinant fusion protein of N-terminal Glutathion-S-Transferase (GST) and full-length human CSNK1D, expressed by baculovirus infected insect cells ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2023
Entry Details
US Patent

TargetCasein kinase I isoform alpha(Human)
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM625275(US20230322767, Example 104 | 2-(4-fluorophenyl)-N-...)
Affinity DataIC50: 7nMAssay Description:Recombinant fusion protein of N-terminal Glutathion-S-Transferase (GST) and full-length human CSNK1A1, expressed by baculovirus infected insect cells...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2023
Entry Details
US Patent

TargetCasein kinase I isoform delta(Human)
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM625275(US20230322767, Example 104 | 2-(4-fluorophenyl)-N-...)
Affinity DataIC50: 11nMAssay Description:Recombinant fusion protein of N-terminal Glutathion-S-Transferase (GST) and full-length human CSNK1D, expressed by baculovirus infected insect cells ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2023
Entry Details
US Patent

TargetEpidermal growth factor receptor(Human)
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM625275(US20230322767, Example 104 | 2-(4-fluorophenyl)-N-...)
Affinity DataIC50: 8.22E+3nMAssay Description:For the assay 50 nl of a 100 fold concentrated solution of the test compound in DMSO was pipetted into either a black low volume 384 well microtiter ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2023
Entry Details
US Patent

TargetEpidermal growth factor receptor(Human)
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM625275(US20230322767, Example 104 | 2-(4-fluorophenyl)-N-...)
Affinity DataIC50: 2.00E+4nMAssay Description:For the assay 50 nl of a 100 fold concentrated solution of the test compound in DMSO was pipetted into either a black low volume 384 well microtiter ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2023
Entry Details
US Patent

TargetEpidermal growth factor receptor(Human)
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM625275(US20230322767, Example 104 | 2-(4-fluorophenyl)-N-...)
Affinity DataIC50: 2.00E+4nMAssay Description:For the assay 50 nl of a 100 fold concentrated solution of the test compound in DMSO was pipetted into either a black low volume 384 well microtiter ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2023
Entry Details
US Patent