BDBM627031 5-(2,5-Difluoro-phenyl)-1,3-dihydro-benzoimidazol-2-one::US11787802, Example 37

SMILES O=c1[nH]c2ccc(-c3cc(F)ccc3F)cc2[nH]1

InChI Key InChIKey=AHXDRAYYIXKPFA-UHFFFAOYSA-N

Data  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 627031   

TargetDNA damage-binding protein 1/Protein cereblon(Human)
C4 Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 627031BDBM627031(US11787802, Example 37 | 5-(2,5-Difluoro-phenyl)-1...)
Affinity DataKd:  10nMAssay Description:1) Optimization of measurement parameters to minimize protein consumption and to minimize the dilution effect and the DMSO content2) Titration measur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2023
Entry Details
US Patent