BDBM628 (2R,4S)-2-[(R)-{[(2,4-dichlorophenyl)methyl]carbamoyl}[1-(pyridin-2-yl)acetamido]methyl]-N-(2-{[(2R,4S)-2-[(R)-{[(2,4-dichlorophenyl)methyl]carbamoyl}[1-(pyridin-2-yl)acetamido]methyl]-5,5-dimethyl-1,3-thiazolidin-4-yl]formamido}ethyl)-5,5-dimethyl-1,3-thiazolidine-4-carboxamide::Penicillin Et(NH)2 Sym dimer ::penicillin deriv. 41

SMILES [H][C@]1(N[C@@H](C(=O)NCCNC(=O)[C@@H]2N[C@]([H])(SC2(C)C)[C@H](NC(=O)Cc2ccccn2)C(=O)NCc2ccc(Cl)cc2Cl)C(C)(C)S1)[C@H](NC(=O)Cc1ccccn1)C(=O)NCc1ccc(Cl)cc1Cl

InChI Key InChIKey=UFCZJNJTAXXEEG-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 628   

TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Glaxo Group Research

LigandPNGBDBM628(Penicillin Et(NH)2 Sym dimer | (2R,4S)-2-[(R)-{[(...)
Affinity DataIC50: 14nMAssay Description:IC50 values were obtained by assaying the enzyme against the synthetic substrate peptide KQGTVSFNFPQIT, which was tritiated at the proline residue, a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2004
Entry Details Article
PubMed