BDBM628691 6-{[(1R)-1-(4-chlorophenyl)-7-fluoro-5-[1-hydroxy-1-(oxan-4-yl)ethyl]-1-{[1- (hydroxymethyl)cyclopropyl]methoxy}-3-oxo-2,3-dihydro-1H-isoindol-2-yl]methyl}pyridine-3- carbonitrile::US20230338337, Compound 89::US20230338337, Compound 90
SMILES CC(O)(C1CCOCC1)c1cc2C(=O)N(Cc3ccc(cn3)C#N)[C@](OCC3(CO)CC3)(c2c(F)c1)c1ccc(Cl)cc1
InChI Key InChIKey=TWMPEOLEJLTRSB-NFCCVXSLSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 628691
Affinity DataIC50: 0.640nMAssay Description:Each assay was performed in a final volume of 20 μL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HCl, pH 8.0 solution; Corning 46...More data for this Ligand-Target Pair
Affinity DataIC50: 11nMAssay Description:Each assay was performed in a final volume of 20 μL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HCl, pH 8.0 solution; Corning 46...More data for this Ligand-Target Pair