BDBM628881 Preparation of 2-[4-(Difluoromethyl)-3-Fluoro-Phenyl]-N-[(2S)-2-Hydroxy-2-(3-Pyridyl)Ethyl]-N-Propyl-Acetamide ::US20230339890, Compound 50

SMILES CCCN(C[C@@H](O)c1cccnc1)C(=O)Cc1ccc(C(F)F)c(F)c1

InChI Key InChIKey=REDUHHMXVDTNLI-UHFFFAOYSA-N

Data  1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 628881   

TargetLanosterol 14-alpha demethylase(Human)
Kineta

US Patent
LigandPNGBDBM628881(Preparation of 2-[4-(Difluoromethyl)-3-Fluoro-Phen...)
Affinity DataIC50: 100nMAssay Description:Method: Recombinant human CYP51A1 (lanosterol-14a-demethylase) enzyme was coexpressed with CYP reductase in bacterial membranes and the fluorescent s...More data for this Ligand-Target Pair
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Date in BDB:
12/10/2023
Entry Details
US Patent