BDBM629324 US20230339981, Example 4

SMILES F[C@H]1CN2CCC[C@@]2(COc2nc3N4C[C@H]5CC[C@H](N5)[C@H]4COc4nc(c(F)c(n2)c34)-c2cccc3ccc(F)c(C#C)c23)C1

InChI Key InChIKey=JTAUMIJPRRULAD-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 629324   

TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Usona Institute

Curated by ChEMBL
LigandPNGBDBM629324(US20230339981, Example 4)
Affinity DataIC50: 2nMAssay Description:Inhibition of ERK1/2 phosphorylation in human PANC-1 cells incubated for 3 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetGTPase KRas [G12D](Human)
Gilead Sciences

US Patent
LigandPNGBDBM629324(US20230339981, Example 4)
Affinity DataIC50: 4nMAssay Description:Compounds were tested for binding to GDP-loaded KRAS G12D in a 384-well assay format using a TR-FRET probe displacement assay in buffer consisting of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2023
Entry Details
US Patent