BDBM632 2-[(2R)-2-[(2R,4S)-4-[(2-{[(2R,4S)-2-[(R)-[(carboxymethyl)carbamoyl][(2-phenylphenyl)formamido]methyl]-5,5-dimethyl-1,3-thiazolidin-4-yl]formamido}ethyl)carbamoyl]-5,5-dimethyl-1,3-thiazolidin-2-yl]-2-[(2-phenylphenyl)formamido]acetamido]acetic acid::Penicillin Et(NH)2 Sym dimer ::penicillin deriv. 45

SMILES [H][C@]1(N[C@@H](C(=O)NCCNC(=O)[C@@H]2N[C@]([H])(SC2(C)C)[C@H](NC(=O)c2ccccc2-c2ccccc2)C(=O)NCC(O)=O)C(C)(C)S1)[C@H](NC(=O)c1ccccc1-c1ccccc1)C(=O)NCC(O)=O

InChI Key InChIKey=JQBRNXDUXTYTKY-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 632   

TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Glaxo Group Research

LigandPNGBDBM632(2-[(2R)-2-[(2R,4S)-4-[(2-{[(2R,4S)-2-[(R)-[(carbox...)
Affinity DataIC50: 39nMAssay Description:IC50 values were obtained by assaying the enzyme against the synthetic substrate peptide KQGTVSFNFPQIT, which was tritiated at the proline residue, a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2004
Entry Details Article
PubMed