BDBM632956 US20230348453, Compound C4
SMILES Cc1nc(Nc2ncc(s2)C(=O)Nc2c(C)cncc2Cl)cc(n1)N1CCN(CCO)CC1
InChI Key InChIKey=TZEWBPGVTYPITP-UHFFFAOYSA-N
Data 5 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 19 hits for monomerid = 632956
Affinity DataIC50: 1.5nMAssay Description:The IC50 for the inhibition of ABL1 by dasatinib, by C7 and by B3 is approximately 1.5 nM, 5.1 nM and 1.6 nM, and of SRC is 1.5 nM, 1.5 nM and 1.5 nM...More data for this Ligand-Target Pair
Affinity DataIC50: 1.5nMAssay Description:Briefly, a radiometric protein kinase assay (33PanQinase® Activity Assay) was used for measuring the kinase activity of the five protein kinases. All...More data for this Ligand-Target Pair
Affinity DataIC50: 17.7nMAssay Description:Briefly, a radiometric protein kinase assay (33PanQinase® Activity Assay) was used for measuring the kinase activity of the five protein kinases. All...More data for this Ligand-Target Pair
Affinity DataIC50: 17.7nMAssay Description:The IC50 for the inhibition of ABL1 by dasatinib, by C7 and by B3 is approximately 1.5 nM, 5.1 nM and 1.6 nM, and of SRC is 1.5 nM, 1.5 nM and 1.5 nM...More data for this Ligand-Target Pair
Affinity DataIC50: 32.7nMAssay Description:The IC50 for the inhibition of ABL1 by dasatinib, by C7 and by B3 is approximately 1.5 nM, 5.1 nM and 1.6 nM, and of SRC is 1.5 nM, 1.5 nM and 1.5 nM...More data for this Ligand-Target Pair
Affinity DataIC50: 32.7nMAssay Description:Briefly, a radiometric protein kinase assay (33PanQinase® Activity Assay) was used for measuring the kinase activity of the five protein kinases. All...More data for this Ligand-Target Pair
Affinity DataIC50: 130nMAssay Description:The IC50 for the inhibition of ABL1 by dasatinib, by C7 and by B3 is approximately 1.5 nM, 5.1 nM and 1.6 nM, and of SRC is 1.5 nM, 1.5 nM and 1.5 nM...More data for this Ligand-Target Pair
Affinity DataIC50: 130nMAssay Description:Briefly, a radiometric protein kinase assay (33PanQinase® Activity Assay) was used for measuring the kinase activity of the five protein kinases. All...More data for this Ligand-Target Pair
Affinity DataIC50: 677nMAssay Description:The IC50 for the inhibition of ABL1 by dasatinib, by C7 and by B3 is approximately 1.5 nM, 5.1 nM and 1.6 nM, and of SRC is 1.5 nM, 1.5 nM and 1.5 nM...More data for this Ligand-Target Pair
Affinity DataIC50: 677nMAssay Description:Briefly, a radiometric protein kinase assay (33PanQinase® Activity Assay) was used for measuring the kinase activity of the five protein kinases. All...More data for this Ligand-Target Pair
Affinity DataIC50: 9.20E+3nMAssay Description:Briefly, a radiometric protein kinase assay (33PanQinase® Activity Assay) was used for measuring the kinase activity of the five protein kinases. All...More data for this Ligand-Target Pair
Affinity DataIC50: 1.10E+4nMAssay Description:Briefly, a radiometric protein kinase assay (33PanQinase® Activity Assay) was used for measuring the kinase activity of the five protein kinases. All...More data for this Ligand-Target Pair
Affinity DataIC50: 1.32E+4nMAssay Description:Briefly, a radiometric protein kinase assay (33PanQinase® Activity Assay) was used for measuring the kinase activity of the five protein kinases. All...More data for this Ligand-Target Pair
Affinity DataIC50: 1.52E+4nMAssay Description:Briefly, a radiometric protein kinase assay (33PanQinase® Activity Assay) was used for measuring the kinase activity of the five protein kinases. All...More data for this Ligand-Target Pair
Affinity DataIC50: 1.94E+4nMAssay Description:Briefly, a radiometric protein kinase assay (33PanQinase® Activity Assay) was used for measuring the kinase activity of the five protein kinases. All...More data for this Ligand-Target Pair
Affinity DataIC50: 4.56E+4nMAssay Description:Briefly, a radiometric protein kinase assay (33PanQinase® Activity Assay) was used for measuring the kinase activity of the five protein kinases. All...More data for this Ligand-Target Pair
Affinity DataIC50: 5.16E+4nMAssay Description:Briefly, a radiometric protein kinase assay (33PanQinase® Activity Assay) was used for measuring the kinase activity of the five protein kinases. All...More data for this Ligand-Target Pair
Affinity DataIC50: 1.89E+5nMAssay Description:Briefly, a radiometric protein kinase assay (33PanQinase® Activity Assay) was used for measuring the kinase activity of the five protein kinases. All...More data for this Ligand-Target Pair
Affinity DataIC50: 2.34E+7nMAssay Description:Briefly, a radiometric protein kinase assay (33PanQinase® Activity Assay) was used for measuring the kinase activity of the five protein kinases. All...More data for this Ligand-Target Pair