BDBM633514 4-[6-amino-1-[(2,6-difluorophenyl)methyl]pyrazolo[3,4-d]pyrimidine-4-yl]pyridine-2-carbonitrile ::US11806350, Compound 234::US12606564, Compound 234
SMILES Nc1nc(-c2ccnc(c2)C#N)c2cnn(Cc3c(F)cccc3F)c2n1
InChI Key InChIKey=FNXNWVCPMOWTFP-UHFFFAOYSA-N
Data 4 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 633514
Affinity DataKi: 600nMAssay Description:Test compound is weighed, dissolved in DMSO to make a stock solution of 10 mM, diluted with DMSO to prepare working solutions, then 100-fold diluted ...More data for this Ligand-Target Pair
Affinity DataKi: 600nMAssay Description:JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...More data for this Ligand-Target Pair
Affinity DataKi: 5.50E+3nMAssay Description:Test compound is weighed, dissolved in DMSO to make a stock solution of 10 mM, diluted with DMSO to prepare working solutions, then 100-fold diluted ...More data for this Ligand-Target Pair
Affinity DataKi: 5.50E+3nMAssay Description:JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...More data for this Ligand-Target Pair