BDBM634376 4-(oxolan-3-yl)-8,14-dioxa-10,19,20-::US20230357269, Example 61

SMILES O=C(NCCCOc1ccc2[nH]ncc2c1)OCc1cccc(c1)C1CCOC1

InChI Key InChIKey=LKJGGOPYRUOSCW-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 634376   

TargetLeucine-rich repeat serine/threonine-protein kinase 2(Human)
Les Laboratoires Servier

US Patent
LigandPNGBDBM634376(US20230357269, Example 61 | 4-(oxolan-3-yl)-8,14-d...)
Affinity DataIC50: 10nMAssay Description:LRRK2 Kinase reactions were carried out in 384-well white polystyrene plates in a final volume of 6 μl using ADP-Glo Kinase Assay kit (Promega C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2024
Entry Details
US Patent