BDBM6345 2-(phenylamino)-8-(propan-2-yl)quinazolin-7-ol::2-Aminoquinazoline 24

SMILES CC(C)c1c(O)ccc2cnc(Nc3ccccc3)nc12

InChI Key InChIKey=ZNEYFIGWZSINHD-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 6345   

TargetCyclin-A2/Cyclin-dependent kinase 2(Human)
Naeja Pharmaceutical

LigandPNGBDBM6345(2-(phenylamino)-8-(propan-2-yl)quinazolin-7-ol | 2...)
Affinity DataIC50: 250nMAssay Description:The enzyme was assayed with substrate GST- retinoblastoma in the presence of 12 uM ATP/[gamma-32P] ATP. IC50 is the inhibitor concentration, which in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2005
Entry Details Article
PubMed
LigandPNGBDBM6345(2-(phenylamino)-8-(propan-2-yl)quinazolin-7-ol | 2...)
Affinity DataIC50: 325nMAssay Description:The enzyme was assayed with substrate GST- retinoblastoma in the presence of 12 uM ATP/[gamma-32P] ATP. IC50 is the inhibitor concentration, which in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2005
Entry Details Article
PubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Human)
Naeja Pharmaceutical

LigandPNGBDBM6345(2-(phenylamino)-8-(propan-2-yl)quinazolin-7-ol | 2...)
Affinity DataIC50: 550nMAssay Description:The enzyme was assayed with substrate GST- retinoblastoma in the presence of 12 uM ATP/[gamma-32P] ATP. IC50 is the inhibitor concentration, which in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2005
Entry Details Article
PubMed
LigandPNGBDBM6345(2-(phenylamino)-8-(propan-2-yl)quinazolin-7-ol | 2...)
Affinity DataIC50: 813nMAssay Description:The enzyme was assayed with substrate GST- retinoblastoma in the presence of 12 uM ATP/[gamma-32P] ATP. IC50 is the inhibitor concentration, which in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2005
Entry Details Article
PubMed