BDBM634868 US11814367, Compound 317

SMILES F[C@@H]1C[C@H](N(C1)C(=O)Cn1ncc(n1)N1CCC1)C(=O)N[C@@H](c1ccccc1)c1ccc(C2CC2)c(F)n1

InChI Key InChIKey=MFFKBDYVRYZYPY-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 634868   

TargetGlycogen [starch] synthase, muscle(Human)
Maze Therapeutics

US Patent
LigandPNGBDBM634868(US11814367, Compound 317)
Affinity DataIC50: 17nMAssay Description:Compounds that inhibit the hGYS1 enzyme and, subsequently, the downstream conversion of NADH to NAD+, were tested using assay ready plates (black, cl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/8/2024
Entry Details
US Patent

TargetGlycogen [starch] synthase, liver(Human)
Maze Therapeutics

US Patent
LigandPNGBDBM634868(US11814367, Compound 317)
Affinity DataIC50: 1.00E+5nMAssay Description:Compounds that inhibit the hGYS2 enzyme and, subsequently, the downstream conversion of NADH to NAD+, were tested using assay ready plates (black, cl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/8/2024
Entry Details
US Patent