BDBM636355 US20230365546, Compound 138

SMILES CC(C)C(=O)Nc1nc2cc(ccn2n1)-c1ccc2n(C)cc(C(=O)NC(C)c3cccnc3)c2c1

InChI Key InChIKey=KETSBXFPWUCVED-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 636355   

TargetReceptor-interacting serine/threonine-protein kinase 1(Human)TBA

LigandBDBM636355(US20230365546, Compound 138)Copy SMILESCopy InChI

Affinity DataIC50: 87nMAssay Description:Inhibition of human RIPK1 (1 to 294 residues) preincubated for 15 mins followed by [gamma-33P]ATP addition and measured after 40 mins by scintillatio...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProtUniProtKB/TrEMBL
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Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
TBA
Entry Details
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TargetReceptor-interacting serine/threonine-protein kinase 1(Human)TBA

LigandBDBM636355(US20230365546, Compound 138)Copy SMILESCopy InChI

Affinity DataIC50: 1.00E+3nMAssay Description:In vitro kinase assays were conducted using Kinase Profiler services provided by Eurofins. The experimental method was as follows: the small molecule...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProtUniProtKB/TrEMBL
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
1/12/2024
Entry Details
Copy BDB DOIUS Patent

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