BDBM637109 US20230382904, Compound 29::US20230382904, Compound 54::US20230382904, Compound 55
SMILES C[C@H](NC(=O)c1cc(cs1)-c1cc(C(=O)NC2CNC(=O)C2)c2nc(N)nn2c1)c1ccccc1
InChI Key InChIKey=XZJAQIDXESVVQD-CWQZNGJJSA-N
Data 6 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 637109
Affinity DataIC50: 2.80nMAssay Description:Assay Protocol for 1536 MTP format: test compounds were predispensed (60 nl) in test plates; +3 μl DLK solution (10 nM DLK, catalytic domain, Ca...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase 13(Homo sapiens (Human))
The Johns Hopkins University
US Patent
The Johns Hopkins University
US Patent
Affinity DataIC50: 60nMAssay Description:Assay Protocol for 384 low volume MTP format: 1 μl of test compound was pipetted into test plate; +5 μl LZK solution (10 nM LZK, catalytic ...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase 13(Homo sapiens (Human))
The Johns Hopkins University
US Patent
The Johns Hopkins University
US Patent
Affinity DataIC50: 6.50E+3nMAssay Description:Assay Protocol for 384 low volume MTP format: 1 μl of test compound was pipetted into test plate; +5 μl LZK solution (10 nM LZK, catalytic ...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase 13(Homo sapiens (Human))
The Johns Hopkins University
US Patent
The Johns Hopkins University
US Patent
Affinity DataIC50: 30nMAssay Description:Assay Protocol for 384 low volume MTP format: 1 μl of test compound was pipetted into test plate; +5 μl LZK solution (10 nM LZK, catalytic ...More data for this Ligand-Target Pair
Affinity DataIC50: 88nMAssay Description:Assay Protocol for 1536 MTP format: test compounds were predispensed (60 nl) in test plates; +3 μl DLK solution (10 nM DLK, catalytic domain, Ca...More data for this Ligand-Target Pair
Affinity DataIC50: 2.30nMAssay Description:Assay Protocol for 1536 MTP format: test compounds were predispensed (60 nl) in test plates; +3 μl DLK solution (10 nM DLK, catalytic domain, Ca...More data for this Ligand-Target Pair