BDBM637765 6-(2-(3-(2- cyclopropyl-1H- imidazol-1- yl)phenoxy)ethoxy)- 5- fluoronicotinonitrile::US11834430, Compound 83

SMILES Fc1cc(cnc1OCCOc1cccc(c1)-n1ccnc1C1CC1)C#N

InChI Key InChIKey=MMQACSOHGPLNRT-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 637765   

TargetProtein-S-isoprenylcysteine O-methyltransferase(Human)
Agency For Science, Technology and Research

US Patent
LigandPNGBDBM637765(US11834430, Compound 83 | 6-(2-(3-(2- cyclopropyl-...)
Affinity DataIC50: 3.70nMAssay Description:An ICMT enzymatic assay was developed using Promega's Methyltransferase-GloTMreagents. In the assay, ICMT catalyzes the methylation of the N-Acet...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2024
Entry Details
US Patent