BDBM639325 Cis or trans-5-fluoro-N-(4- hydroxy-1-methyl- cyclohexyl)-7-[2-(2,2,2- trifluoroethoxy)phenyl] benzofuran-2-carboxamide::US20230391758, Compound 27

SMILES C[C@@]1(CC[C@H](O)CC1)NC(=O)c1cc2cc(F)cc(-c3ccccc3OCC(F)(F)F)c2o1

InChI Key InChIKey=PYCXYSVFJYKTBD-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 639325   

TargetCeramide glucosyltransferase(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM639325(Cis or trans-5-fluoro-N-(4- hydroxy-1-methyl- cycl...)
Affinity DataEC50:  0.240nMAssay Description:Using Promega's UDP-Glo™ Glycosyltransferase assay kit (Promega Corporation, Madison, WI, USA (Promega)), GCS activity was indirectly measur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2024
Entry Details
US Patent