BDBM639352 2-(1-Methyl-1H-imidazol-2-yl)ethyl 3-{[(5-chloro-2-thienyl)carbonyl]amino}-N-({2-ethyl-3-[(3S)-3-hydroxy-2-oxopyrrolidin-1-yl]phenyl}sulfonyl)-S-alaninate methanesulfonate::US20230391761, Example 4

SMILES COCC12CC(n3ncc(Nc4ncc5cc(Cl)c(C6CCN(C7COC7)CC6)cc5n4)c3C)(C1)C2

InChI Key InChIKey=UHRIYOJEACOYON-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 639352   

TargetLeucine-rich repeat serine/threonine-protein kinase 2(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 639352BDBM639352(6-chloro-N-{1-[3- (methoxymethyl)bicyclo[1.1.1] pe...)
Affinity DataIC50: 0.631nMAssay Description:The ability of compounds to modulate production of amyloid beta protein Abeta(1-42) was determined using human WT-APP overexpressing CHO cells. Cells...More data for this Ligand-Target Pair
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Date in BDB:
6/15/2026
Entry Details US Patent