BDBM6400 5-[6-(3-Chloro-phenylamino)-pyrazin-2-yl]-N-(3-hydroxy-propyl)-nicotinamide::5-{6-[(3-chlorophenyl)amino]pyrazin-2-yl}-N-(3-hydroxypropyl)pyridine-3-carboxamide::Pyrazine-Pyridine Biheteroaryl 43

SMILES OCCCNC(=O)c1cncc(c1)-c1cncc(Nc2cccc(Cl)c2)n1

InChI Key InChIKey=CQKZPPUFUROCPO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 6400   

TargetVascular endothelial growth factor receptor 2(Rat)
Johnson & Johnson Pharmaceutical

LigandPNGBDBM6400(5-[6-(3-Chloro-phenylamino)-pyrazin-2-yl]-N-(3-hyd...)
Affinity DataIC50: 2.38E+3nMAssay Description:The enzyme was assayed with a biotinylated peptide substrate and test compounds in the presence of 5 uM ATP/[gamma-33P]ATP in a streptavidin coated F...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2005
Entry Details Article
PubMed
TargetCyclin-dependent kinase/G2/mitotic-specific cyclin- 1(Human)
Johnson & Johnson Pharmaceutical

LigandPNGBDBM6400(5-[6-(3-Chloro-phenylamino)-pyrazin-2-yl]-N-(3-hyd...)
Affinity DataIC50: 1.00E+4nMAssay Description:The enzyme was assayed with a biotinylated peptide substrate and test compounds in the presence of 5 uM ATP/[gamma-33P]ATP in a streptavidin coated F...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2005
Entry Details Article
PubMed