BDBM640975 US20230399342, Example 50

SMILES C[C@@H]1CN([C@@H](C)CN1C(C1CC(F)(F)C1)c1ccc(Cl)c(F)c1)c1nc2nncn2c2n(C[C@@H]3CCCO3)c(C)nc12

InChI Key InChIKey=NCJOUSGGFHXXOR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 640975   

TargetDiacylglycerol kinase zeta(Human)
Incyte

US Patent
LigandPNGBDBM640975(US20230399342, Example 50 | US20250186450, Example...)
Affinity DataIC50: 20nMAssay Description:The DGKα and DGKζ biochemical reactions were performed using His-tagged human recombinant enzymes (Signal Chem, DGKα, #D21-10BH; DGKζ, #D30-10H)) and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2025
Entry Details
US Patent

TargetDiacylglycerol kinase alpha(Human)
Incyte

US Patent
LigandPNGBDBM640975(US20230399342, Example 50 | US20250186450, Example...)
Affinity DataIC50: 20nMAssay Description:The DGKα and DGKζ biochemical reactions were performed using His-tagged human recombinant enzymes (Signal Chem, DGKα, #D21-10BH; DGKζ, #D30-10H)) and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2025
Entry Details
US Patent

TargetDiacylglycerol kinase alpha(Human)
Incyte

US Patent
LigandPNGBDBM640975(US20230399342, Example 50 | US20250186450, Example...)
Affinity DataIC50: 20nMAssay Description:The DGKα and DGKξ biochemical reactions were performed using His-tagged human recombinant enzymes (Signal Chem, DGKα, #D21-1OBH; DGK&#...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/3/2024
Entry Details
US Patent

TargetDiacylglycerol kinase zeta(Human)
Incyte

US Patent
LigandPNGBDBM640975(US20230399342, Example 50 | US20250186450, Example...)
Affinity DataIC50: 20nMAssay Description:The DGKα and DGKξ biochemical reactions were performed using His-tagged human recombinant enzymes (Signal Chem, DGKα, #D21-1OBH; DGK&#...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/3/2024
Entry Details
US Patent