BDBM642339 N-[(3S)-5,5-difluoropiperidin-3-yl]-2-{5-[(3- ethoxypyridin-2-yl)oxy]pyridin-3- yl}pyrimidine-5-carboxamide::US20230405002, Example 19

SMILES CCOc1cccnc1Oc1cncc(c1)-c1ncc(cn1)C(=O)N[C@H]1CNCC(F)(F)C1

InChI Key InChIKey=STEOFTXCZZHZJZ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 642339   

TargetDiacylglycerol O-acyltransferase 2(Human)
Pfizer

US Patent
LigandPNGBDBM642339(N-[(3S)-5,5-difluoropiperidin-3-yl]-2-{5-[(3- etho...)
Affinity DataIC50: 240nMAssay Description:For determination of IC50 values, the reactions were carried out in 384-well white polypropylene plates (Nunc) in a total volume of 20 μL. To 1 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/12/2024
Entry Details
US Patent