BDBM6425 3-[(6-amino-5-{6-[(3-chlorophenyl)amino]pyrazin-2-yl}pyridin-3-yl)amino]propan-1-ol::3-{6-Amino-5-[6-(3-chloro-phenylamino)-pyrazin-2-yl]-pyridin-3-ylamino}-propan-1-ol::Pyrazine-Pyridine Biheteroaryl 79

SMILES Nc1ncc(NCCCO)cc1-c1cncc(Nc2cccc(Cl)c2)n1

InChI Key InChIKey=HWMHBHCITCJTIA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 6425   

TargetVascular endothelial growth factor receptor 2(Rat)
Johnson & Johnson Pharmaceutical

LigandPNGBDBM6425(3-[(6-amino-5-{6-[(3-chlorophenyl)amino]pyrazin-2-...)
Affinity DataIC50: 1.36E+3nMAssay Description:The enzyme was assayed with a biotinylated peptide substrate and test compounds in the presence of 5 uM ATP/[gamma-33P]ATP in a streptavidin coated F...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2005
Entry Details Article
PubMed
TargetCyclin-dependent kinase/G2/mitotic-specific cyclin- 1(Human)
Johnson & Johnson Pharmaceutical

LigandPNGBDBM6425(3-[(6-amino-5-{6-[(3-chlorophenyl)amino]pyrazin-2-...)
Affinity DataIC50: 1.00E+4nMAssay Description:The enzyme was assayed with a biotinylated peptide substrate and test compounds in the presence of 5 uM ATP/[gamma-33P]ATP in a streptavidin coated F...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2005
Entry Details Article
PubMed