BDBM644416 5-((2-(4-((3-chloro-4- cyclobutoxybenzyl) amino)butoxy)ethyl) amino)benzo[c][2,6] naphthyridine- 8-carboxamide::US11866436, Example 10

SMILES NC(=O)c1ccc2c(c1)nc(NCCOCCCCNCc1ccc(OC3CCC3)c(Cl)c1)c1ccncc21

InChI Key InChIKey=SRKWBNXTMZQFGN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 644416   

TargetCasein kinase II subunit alpha [2-329](Human)
Cambridge Enterprise

US Patent
LigandPNGBDBM644416(US11866436, Example 10 | 5-((2-(4-((3-chloro-4- cy...)
Affinity DataIC50: 0.372nMAssay Description:Final assay conditions comprised 0.2 nM CK2α, 50 μM peptide substrate (RRRADDSDDDDD), 15 μM ATP in 1× reaction buffer (40 mM Tris pH7....More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2024
Entry Details
US Patent

TargetDual specificity protein kinase CLK2(Human)
Cambridge Enterprise

US Patent
LigandPNGBDBM644416(US11866436, Example 10 | 5-((2-(4-((3-chloro-4- cy...)
Affinity DataIC50: 408nMAssay Description:The assay was conducted in the same way as described for CK2α, with final assay conditions comprising 20 nM CLK2 (Carna Biosciences-04-127), 50 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2024
Entry Details
US Patent