BDBM644500 5-(2-(4-((3- (cyanomethyl)- 5- fluorobenzyl) amino)butoxy) ethoxy)benzo[c] [2,6]naphthy- ridine-8- carboxylic acid::US11866436, Example 95

SMILES OC(=O)c1ccc2c(c1)nc(OCCOCCCCNCc1cc(F)cc(CC#N)c1)c1ccncc21

InChI Key InChIKey=WTHVHUDPRPCKCA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 644500   

TargetCasein kinase II subunit alpha [2-329](Human)
Cambridge Enterprise

US Patent
LigandPNGBDBM644500(US11866436, Example 95 | 5-(2-(4-((3- (cyanomethyl...)
Affinity DataIC50: 0.418nMAssay Description:Final assay conditions comprised 0.2 nM CK2α, 50 μM peptide substrate (RRRADDSDDDDD), 15 μM ATP in 1× reaction buffer (40 mM Tris pH7....More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2024
Entry Details
US Patent

TargetDual specificity protein kinase CLK2(Human)
Cambridge Enterprise

US Patent
LigandPNGBDBM644500(US11866436, Example 95 | 5-(2-(4-((3- (cyanomethyl...)
Affinity DataIC50: 170nMAssay Description:The assay was conducted in the same way as described for CK2α, with final assay conditions comprising 20 nM CLK2 (Carna Biosciences-04-127), 50 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2024
Entry Details
US Patent