BDBM645017 US11981682, Example 2-1::US20240010658, Example 2-1

SMILES Brc1ccc(N[C@@H]2CC[C@H]3CN(C[C@@H]23)C(=O)c2cc3COCCc3s2)nn1

InChI Key InChIKey=NBJZETZOSUFBNB-IACUBPJLSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 645017   

TargetMonoacylglycerol lipase ABHD6 [33-337](Human)
Ono Pharmaceutical Co.

US Patent
LigandPNGBDBM645017(US11981682, Example 2-1 | US20240010658, Example 2...)
Affinity DataIC50:  1nMAssay Description:First, 1-arachidonoyl glycerol (Cayman Chemical) as a substrate was prepared with an assay buffer containing 50 mM tris-HCl (pH 7.4), 100 mM NaCl, an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetMonoacylglycerol lipase ABHD6(Human)
Ono Pharmaceutical Co.

US Patent
LigandPNGBDBM645017(US11981682, Example 2-1 | US20240010658, Example 2...)
Affinity DataIC50:  3nMAssay Description:The binding affinity of the test compound for human ABHD6 was measured using bioluminescence resonance energy transfer (hereinafter, abbreviated as B...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetMonoacylglycerol lipase ABHD6(Human)
Ono Pharmaceutical Co.

US Patent
LigandPNGBDBM645017(US11981682, Example 2-1 | US20240010658, Example 2...)
Affinity DataIC50:  1nMAssay Description:First, 1-arachidonoyl glycerol (Cayman Chemical) as a substrate was prepared with an assay buffer containing 50 mM tris-HCl (pH 7.4), 100 mM NaCl, an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent