BDBM645029 US11981682, Example 10::US20240010658, Example 10

SMILES Cc1ccc(s1)C(=O)N1C[C@@H]2CC[C@@H](Nc3ccc(Br)nn3)[C@]2(F)C1

InChI Key InChIKey=CRUZZTJYBYOPJL-PPHDSNJXSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 645029   

TargetMonoacylglycerol lipase ABHD6 [33-337](Human)
Ono Pharmaceutical Co.

US Patent
LigandPNGBDBM645029(US11981682, Example 10 | US20240010658, Example 10)
Affinity DataIC50: <1nMAssay Description:First, 1-arachidonoyl glycerol (Cayman Chemical) as a substrate was prepared with an assay buffer containing 50 mM tris-HCl (pH 7.4), 100 mM NaCl, an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetMonoacylglycerol lipase ABHD6(Human)
Ono Pharmaceutical Co.

US Patent
LigandPNGBDBM645029(US11981682, Example 10 | US20240010658, Example 10)
Affinity DataIC50:  2nMAssay Description:The binding affinity of the test compound for human ABHD6 was measured using bioluminescence resonance energy transfer (hereinafter, abbreviated as B...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetMonoacylglycerol lipase ABHD6(Human)
Ono Pharmaceutical Co.

US Patent
LigandPNGBDBM645029(US11981682, Example 10 | US20240010658, Example 10)
Affinity DataIC50: <1nMAssay Description:First, 1-arachidonoyl glycerol (Cayman Chemical) as a substrate was prepared with an assay buffer containing 50 mM tris-HCl (pH 7.4), 100 mM NaCl, an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent